About MethamphetamineMethamphetamine is a highly addictive synthetic stimulant that affects the pleasure centers of the brain. It is considered one of the most highly addictive substances known.
Methamphetamine abuse leads to devastating medical, psychological, and social consequences. Adverse health effects include memory loss, aggression, psychotic behavior, heart damage, malnutrition, and severe dental problems.1
Methamphetamine acts by increasing the release of the neurotransmitter dopamine in the brain, which leads to feelings of euphoria followed by a "crash" that often leads to increased use of the drug and eventually to difficulty feeling any pleasure at all, especially from natural rewards.2
Watch 'Brain & Behavior' to see the impact of methamphetamine on the brain. Developed by UCLA's Integrated Substance Abuse Programs, a leading research institution on the subject of methamphetamine and Eyes of the World Media Group 'Brain & Behavior' provides an inside view of a brain on Meth.
Visit MethProject.org—a definitive source of information about methamphetamine—to learn about the physical, mental, and social effects of Meth use. MethProject.org presents over 350 pieces of content on methamphetamine, ranging from interactive facts, videos, animations, image galleries, polls and quizzes, to personal stories from users, their friends and family, and first-hand accounts from experts.
Meth Impact: National Statistics
This fact sheet provides details on the severity of the Meth crisis nationally.
Methamphetamine Fact Sheet
This fact sheet provides an overview and background on methamphetamine.
2 From the Director: Methamphetamine Abuse and Addiction. NIDA Research Report Series. Volkow, N.D. 2006.